An integrated finite element simulation of cardiomyocyte function based on triphasic theory

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An integrated finite element simulation of cardiomyocyte function based on triphasic theory

In numerical simulations of cardiac excitation-contraction coupling, the intracellular potential distribution and mobility of cytosol and ions have been mostly ignored. Although the intracellular potential gradient is small, during depolarization it can be a significant driving force for ion movement, and is comparable to diffusion in terms of net flux. Furthermore, fluid in the t-tubules is th...

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The theory of contact mechanics deals with stresses and deformations which arise when the surfaces of two solid bodies are brought into contact. In elastic deformation contact occurs over a finite area. A regular method for determining the dimensions of this area is Hertz Contact Model. Appearance of atomic force microscope results in introduction of Contact ...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2015

ISSN: 1664-042X

DOI: 10.3389/fphys.2015.00287